Searchable abstracts of presentations at key conferences in endocrinology

ea0019p137 | Diabetes, Metabolism and Cardiovascular | SFEBES2009

Sucralose ingestion does not elicit a GLP-1, PYY or appetite response in healthy, normal-weight volunteers.

Ford H , Peters V , Sleeth M , Ghatei M , Frost G , Bloom S

Background: Obesity is a disease with disastrous health, social and economic consequence. There is presently a global epidemic of obesity in all age groups and in both developed and developing countries. Understanding the nutrient and chemical sensing mechanisms in the gastro-intestinal tract (GIT) which act to trigger gut hormone release and appetite after food consumption is crucial to be able to devise effective methods to reduce and prevent obesity. Recently, the sweet tas...